Tissue Engineering: Bioprinting of Multiscaled Hepatic Lobules within a Highly Vascularized Construct (Small 13/2020)
نویسندگان
چکیده
منابع مشابه
3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs.
A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound...
متن کاملEngineering Vascularized Human Adipose Tissue
Introduction Due to complications of currently available therapies, the clinical impetus to engineer adipose tissue for the correction of soft tissue defects is high. Unfortunately, poor survival of in vitro-engineered adipose tissue after transplantation is still a major hurdle for clinical use. The main reason for this poor survival is postulated to be insufficient vascularization. In this st...
متن کاملTissue engineering by decellularization and 3D bioprinting
1 Pluripotent Stem Cells and Activation of Endogenous Tissue Programs for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), c/ Baldiri Reixac 15-21, 08028 Barcelona, Spain 2 Institute for Bioengineering of Catalonia (IBEC), c/ Baldiri Reixac 15-21, 08028 Barcelona, Spain; University of Barcelona, Spain Nanotechnology Platform, Institute for Bioengineering of Catalonia (IBEC)...
متن کامل3-dimensional bioprinting for tissue engineering applications.
The 3-dimensional (3D) printing technologies, referred to as additive manufacturing (AM) or rapid prototyping (RP), have acquired reputation over the past few years for art, architectural modeling, lightweight machines, and tissue engineering applications. Among these applications, tissue engineering field using 3D printing has attracted the attention from many researchers. 3D bioprinting has a...
متن کاملThree-dimensional bioprinting of thick vascularized tissues.
The advancement of tissue and, ultimately, organ engineering requires the ability to pattern human tissues composed of cells, extracellular matrix, and vasculature with controlled microenvironments that can be sustained over prolonged time periods. To date, bioprinting methods have yielded thin tissues that only survive for short durations. To improve their physiological relevance, we report a ...
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ژورنال
عنوان ژورنال: Small
سال: 2020
ISSN: 1613-6810,1613-6829
DOI: 10.1002/smll.202070067